The Atlas Computer Laboratory recognised the need to provide expertise in both the computer software being provided and the computer applications that users required. In many cases the staff with application expertise were also researchers in the field themselves.
Some examples are:
| Pat Athawes | Statistics |
| Oliver Atkin | Number Theory |
| John Baldwin | XRay-63, Sigma 2 Front-End |
| Mike Baylis | Engineer's Assistant, Sigma 2 Front-End |
| Alex Bell | Algol, Game Playing |
| Malcolm Bird | Number Theory Programming |
| Paul Bryant | Hartran, SOL, Networking |
| Subodh Chanda | Finite Elements, PAFEC |
| Mike Chiu | MUNICH CI, ATMOL2 |
| Bob Churchhouse | Information Retrieval, Number Theory |
| Lorna Claringbold | Microdensitometer, Optronics Photoscan |
| Brian Cooper | Statistics, ASCOP |
| Jean Crow | Finite Elements, NASTRAN |
| Mike Elder | Microdensitometer, SHEL-X, ORTEP |
| Graham England | D-MAC, PDP-15, SPROGS |
| Bart Fossey | Hartran |
| Alan Francis | CASS, VCS3, CAMP/CAMPER, SPROGS, PDP15 |
| Julian Gallop | SPROGS, PDP15, PIGS |
| Liz Gill | G-EXEC, Geological Data |
| Tim Gover | NERC, Bore hole data |
| Ian Grant | Radiative Transfer |
| Martyn Guest | ATMOL, MUNICH-CI |
| Jim Hailstone | MVC |
| Susan Hockey | COCOA, Greek, Hebrew, Arabic, Persian, Akkadian and Egyptian Fonts, Literary Analysis |
| Frank Hodson | Classification, Archaeology |
| Bob Hopgood | MIDIAT, Algol, Compiler Compiler, GROATS, CAMP/CAMPER |
| Garry Hunt | Radiative Transfer |
| Peter Kent | SOL, Time Series Analysis, BOMM, BOON |
| Judy Lay | MVC |
| John Lewis | Contour Plotting, Physics of Liquids and Solids |
| Fred Lunnon | Number Theory Programming |
| Pella Machin | Microdensitometer, X-RAY, SHEL-X |
| Paul Nelson | SCFOR |
| Susan Powell | Linear Programming |
| Don Russell | COCOA, LISP |
| Vic Saunders | ATMOL, MUNICH-CI |
| Wade Shaw | PIGS |
| Peter Smith | Astronomy |
| Barbara Stokoe | Hartran, Ariel III |
| Peter Sutterlin | G-EXEC |
| Eric Thomas | Sigma 2 Front End, SPROGS |
| Judy Thomas | X-RAY |
| David Toll | GROATS |
| Anton Walter | ASCOP, UK4 |
| Rob Witty | Tree-Meta |
